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High blood pressure and non steroidal anti rheumatics

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Non-steroidal anti-inflammatory drugs, also known as NSAIDs, have analgesic and anti-inflammatory properties. 

They help with head, back and dental pain and are used as anti-inflammatory drugs and are also used for many other forms of pain.

NSAIDs are one of Germany's most widely prescribed drugs. 

Depending on the active substance contained in NSAIDs, they can be available without a prescription and are in particularly high demand for self-medication from pharmacies.

Active ingredients of NSAIDs include ibuprofen, diclofenac and acetylsalicylic acid.

Some also contain paracetamol

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Anti rheumatics - increase the residence of blood vessels

There have been a number of scientific studies dealing with the side effects and interactions of NSAIDs.

One focus of this research is on the influence of non-steroidal anti-inflammatory drugs on blood pressure

It is now clear that NSAIDs can increase the blood pressure and they have been shown to significantly increase and cause high blood pressure.

This is true for people whose blood pressure was initially within the normal range, as well as for patients with hypertension.

The increase in blood pressure with NSAIDs concerns people with high pressure that is being untreated as well as those patients who are taking blood pressure medicine. 

The causes of this phenomenon are not yet fully understood.

But the fact is that NSAIDs increase the resistance in the walls of blood vessels.

The higher resistance means that the blood must be pumped at higher pressure through the veins. 

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An effect of non-steroidal anti-inflammatory drugs can be high blood pressure 

Particularly fatal: NSAIDs such as certain anti-inflammatory drugs affect the effect of blood pressure lowering drugs.

You can reduce the antihypertensive effect of these drugs. 

The effect is dependent on the respective preparations and dose.

Low doses of NSAIDs, for example, 100 mg of aspirin to thin the blood used in conjunction with blood pressure medicine has no negative effect on blood pressure. 

Especially pronounced is the effect on the long-term use of both drugs in relatively high doses.

The highest does in one study using NSAIDs with concomitant administration of blood pressure-lowering drugs was 6.2 mmHg 

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Interaction of anti rheumatics with hypertension

As with many drug interactions, the mechanism of this interaction is not yet fully understood.

When you consider that about 40% of people in Germany suffer from high blood pressure, and many of them are taking blood pressure-lowering agents, the scope can be very large.

With many thousands of hypertensive patients whose blood pressure medicines do not show sufficient effect, NSAIDs could be the cause.

Particularly at risk by the interactions between NSAIDs and blood pressure-lowering drugs are the elderly, who often suffer from both high blood pressure levels as well as from rheumatic pain.


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