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Clevidipine with high blood pressure

Clevidipine and high blood pressure

Clevidipine is a calcium channel blocker and causes a decreased intake of calcium in the muscles of the arteries, but it does not affect the veins so the return of blood to the heart is not disabled. This promotes a relaxation of the muscle cells in blood vessels and arteries, and leads to lower blood pressure. This is because the usual narrowing of the vessels is absent.

Side effects

Frequently occurring side effects include edema and chest pain. Uncommon side effects include fainting, rapid heart rate, profuse urination, weakness, confusion, thirst, loss of appetite, vomiting, palpitations, constipation, aching chest, tied arms, sweating, weak pulse, slow breathing, headaches, visual limitations, fear, confusion and dangerously high blood pressure. It can sometimes also cause intestinal obstruction.

The calcium channel blocker Clevidipine

Clevidipine and hypertension - calcium channel blockers

The calcium antagonist clevidipine helps with hypertension


Interactions between clopidogrel, Clevidipine and indinavir are frequently discussed. But it can cause allergies to soy and eggs as well as problems with fat metabolism.


If you suffer from a pancreatic inflammation, or a constriction of the aorta, then the use of clevidipine is not possible. Clevidipine should also not be used after a heart attack.

In animal studies, the Clevidipine has been found to adversely affect the development of the embryo, so the drug should not be used during pregnancy. Whether Clevidipine is excreted in human milk is not known and it has not been evaluated in animal studies.


- Cleviprex (Solution for injection 0.5 mg / ml)

Here you can read more about the calcium antagonist felodipine and its application in high blood pressure.

The calcium channel blockers clevidipine

Various types of calcium channel blockers

In general there are 2 different types of calcium antagonists (calcium channel blockers), namely the non-dihydropyridine and the dihydropyridines.

Non-dihydropyridines are:

- diltiazem
- gallopamil
- verapamil

Dihydropyridines are:

- Amlodipine
- Clevidipine
- Felodipine
- Isradipine
- Lacidipine
- Lercanidipine
- Manidipine
- Nicardipine
- Nifedipine
- Nilvadipine
- Nimodipine
- Nisoldipine
- Nitrendipine

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