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Diltiazem with high blood pressure

Diltiazem and hypertension

Diltiazem belongs to the calcium channel blockers group and causes the closure of calcium channels, a treatment that has been proven over many years to successfully treat high blood pressure. It acts as a vasodilator and belongs to the group of benzothiazepines.

The antiarrhythmic drug is prescribed in the treatment of high blood pressure, cardiac arrhythmias and to slow down the heart rate in atrial flutter and fibrillation.

Diltiazem is used also used with heart diseases where there is an insufficient oxygen supply to the heart, and for circulatory disorders of the coronary arteries.

Diltiazem has all the properties of the various calcium channel blocker. Blood flow to the heart is enhanced by diltiazem and it dilates the blood vessels and thus lowers high blood pressure. It also has significant effects on the myocardium and can be used for cardiac arrhythmias.

Calcium channel blocker: diltiazem and hypertension

The calcium antagonist Diltiazem helps with hypertension

Diltiazem leads to a sharp drop in blood pressure when it is inserted directly into the vein, but as a result the pulse with increase dramatically.

When taken orally, the pulse remains almost unchanged and the heart is supplied with more blood and therefore more oxygen.

The active ingredient Diltiazem is the Diltiazemi hydrochloricum. A 200 mg capsule (once daily) is used to treat hyperthermia, especially in elderly patients and patients with renal and hepatic insufficiency. If well tolerated, the dose may be increased to 300 mg a day. Diltiazem may be taken at any time during the day, but it should always be about the same time.

In addition, diltiazem acts on the control system of the heart.

Hypersensitivity to diltiazem can cause a weak heart muscle at rest, a sinus node syndrome or a stimulus interruption in the area of the sinus node. If you suffer from heart muscle disorders such as atrial fibrillation or an acute myocardial infarction, then diltiazem should not be used.

Diltiazem is a calcium channel blocker

The effectiveness of diltiazem on children has not yet been investigated. Even the use of diltiazem on pregnant women hasn’t been investigated. In animal studies, however, it has been shown that diltiazem occurs in very small concentrations in breast milk, and there it is not recommended during breastfeeding.

The use of diltiazem should be closely monitored because it can lead to a loss of muscle.

Side effects may include nausea, vomiting, bloating, fatigue, nervousness, muscle pain, joint pain, drowsiness, skin redness, itching, heartburn, diarrhoea, constipation, insomnia, hallucinations and depression. More rarely lymph node swelling, proliferation of white blood cells and gingival overgrowth may occur.

Medications containing the active ingredient diltiazem

At high doses it can cause significant hypotension, hypertension, impotence, erectile dysfunction and heart muscle weakness.

Special care is required in diabetic patients (diabetes), since diltiazem occasionally causes an increase in blood sugar level.

Diltiazem may increase the effects of digoxin, as well as the effect of diuretics.

Drugs include:

- DiltaHEXAL (tablets with 60,90, 120 and 180 mg capsules)

- Diltaretard (capsules with 90.120 and 180 mg)

- Diltazem Heumann (tablet with 60 and 90 mg capsule)

- Diltiazem-ratiopharm (60 mg tablets and capsules with 90.120 and 180 mg)

- Diltiazem Stada (capsules with 90.120 and 180 mg)

- Dilzem (90.120 tablets and 180 mg capsules, and 180 and 240 mg)

Here you can read more about the calcium antagonist gallopamil and its application in high blood pressure.




The calcium channel blockers diltiazem for hypertension




Diltiazem is a calcium channel blocker




Medications containing the active ingredient diltiazem




Various types of calcium channel blockers

In general there are 2 different types of calcium antagonists (calcium channel blockers), namely the non-dihydropyridine and the dihydropyridines.

Non-dihydropyridines are:

- diltiazem
- gallopamil
- verapamil

Dihydropyridines are:

- Amlodipine
- Clevidipine
- Felodipine
- Isradipine
- Lacidipine
- Lercanidipine
- Manidipine
- Nicardipine
- Nifedipine
- Nilvadipine
- Nimodipine
- Nisoldipine
- Nitrendipine




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