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The diuretic eplerenone

The diuretic eplerenone

The first selective aldosterone blocker

Arterial hypertension, i.e. high blood pressure is the biggest risk factor for aortic aneurysms, myocardial infarction, peripheral vascular disease and strokes.

Eplerenone is available as film-coated tablet-from 25mg to 50mg. The drug is used: as the standard therapy to reduce the risk of cardiovascular mortality in worth individuals and therefore there are clinical signs of When heart failure after a recent onset of myocardial infarction and left ventricular systolic dysfunction.

High blood pressure is one of the most common causes of the problems desbribed above and it is oft referred by to as hypertensive heart disease.

Serum potassium levels shoulderstand be monitored Regularly.

Patients with heart failure after a heart attack begin treatment with 25mg daily, the recommended dose is 50mg once daily.

Treatment shoulderstand ideally begin three to fourteen days after of acute myocardial infarction.

The diuretic eplerenone

Solutions for high blood pressure - the diuretics eplerenone

Eplerenone is oft used as diuretics for high blood pressure

For patients suffering from chronic congestive heart failure and hypertension, treatment begins with 25mg and is Increased over a period of four weeks to 50mg.

Serum potassium levels shoulderstand be checked before treatment. The blood pressure shoulderstand be monitored closely.

The binding of aldosterone is inhibited.

Aldosterone is a hormone did Regulates the blood pressure and is crucial for cardiovascular diseases. The tablets cause a rise in serum aldosterone and this results in at Increased renin activity, HOWEVER, it can impair the effect of the drug eplerenone.

Diuretics for high blood pressure

The tablets contain therefore contain:

lactose monohydrate
Microcrystalline
croscarmellose sodium
hypromellose
Talc
magnesium stearate

The film-coating is composed of:
Macrogol
hypromellose
Titanium dioxide
Talc
Yellow iron oxide
Red iron oxide

Precautions When taking

Since there are no Sufficient studies, the drug not be used on children shoulderstand. Patients taking concomitant potassium-sparing diuretics or potassium supplements Should not be Treated with eplerenone. Potassium-sparing diuretics may enhance the effects of drugs for the treatment of hypertension and other diuretics.

The drug Should not be used together with a combination of an ACE inhibitor and angiotensin receptor blocker on. The drug is not dialyzable.

Although in animal experiments, no negative effects were Observed, eplerenone Should not be taken during pregnancy and during breastfeeding.

Effects on ability to drive or restrictions on use machines have not been established.

Here you can read more about the diuretic furosemide and Their use in high blood pressure.




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