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Agent fosinopril in hypertension

Fosinopril and the group of ACE inhibitors

Fosinopril comes from the family of ACE inhibitors and it is an antihypertensive drug which is also used in the treatment of heart failure, and myocardial infarctions.

In hypertensive patients, the drug can be used as both a single agent and can also be combined with other drugs.

In cardiac muscle weaknesses, a combination of drugs are often used.

Patients who are treated after suffering from a heart attack are usually treated with ACE inhibitors (including Fosinopril) and they have a significantly lower risk of death.

Unlike beta-blockers and calcium channel blockers, ACE inhibitors do not change the heartbeat or pulse rate.

Thus, most patients can tolerate ACE inhibitors better than other antihypertensive agents.

However, a side effect of taking ACE inhibitors, such as Fosinopril, can lead to a mild (and in some cases a very strong) urge to cough.

Fosinopril is based on the inhibition of ACE (angiotensin converting enzyme) produced in the kidney and thus reduces the formation of angiotensin II.

Angiotensin II causes the constriction of blood vessels and therefore increases the blood pressure.



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Fosinopril in use against hypertension

The fosinopril as ACE inhibitors in hypertension
Fosinopril in hypertension

An ACE inhibitors such as Fosinopril, lowers blood pressure and provides heart relief.

In addition, ACE inhibitors will increase the amount of salt and water that is excreted from your body and further help to lower your blood pressure.

Trade names are:

- Fosinorm (10 and 20 mg tablets)

- Dynacil (5,10 and 20 mg tablets)

- Fosino Teva (10 and 20 mg tablets)

Ingestion:

Should be taken once daily (always at the same time) and independently of mealtimes.

Side effects:

The best-known common side effects of Fosinopril are shortness of breath, skin rashes, renal dysfunction, headaches, fatigue, coughs, weakness, dizziness, hypersensitivity and indigestion issues.




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Rarely occurring side effects of fosinopril

There are some rarer side effects including a reduction in the number of white blood cells or platelets, diarrhoea or constipation, an increased excretion of protein in the urine, a deficiency of blood cells, skin inflammations, allergic skin reactions and itching.

Moreover, some patients report a swelling of the vessels, impaired consciousness, fainting, depression, sleep disorders, balance problems, visual disturbances, an increased formation of urine, hives and a few others.

Less common are heart palpitations, angina pectoris, inflammation of the liver or the lungs, fever, muscle and joint pain, inflammation of the blood vessels, hair loss, anaemia, stroke and heart attacks.




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Interactions with fosinopril

Fosinopril can interact with painkillers, anti-inflammatory drugs, anaesthetic agents, immunosuppressive agents, agents that increase the levels of potassium, insulin and agents that are used against diabetes and with sodium chloride.

Warnings:

Upon the occurrence of fever, inflammation, dizziness, nausea, you should immediately contact your doctor.

Moreover, it is sufficient to drink a lot of water with fosinopril and not to discontinue therapy abruptly, or without medical advice.

Fosinopril may cause malformations in embryos.


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ACE inhibitors in an overview

Other drugs in this group are listed here alphabetically. 

For more information, simply click on the link

Benazepril (Lotensin)

Captopril (Capoten)

Cilazapril

Enalapril (Vasotec)

Fosinopril (Monopril)

Lisinopril (Prinivil, Zestril)

Moexipril

Perindopril

Quinapril (Accupril)

Ramipril (Altace)

Spirapril

Trandolapril

Zofrenopril

Also note that the ACE inhibitors are often used in combination with other blood pressure lowering drugs. 

Here you read about the so-called combination therapy in hypertension.


What kind of drugs for treating high blood pressure?