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Isradipine with high blood pressure

Isradipine and hypertension

Isradipine is a calcium channel blocker from the group of Dihydropyidine and is used for lowering high blood pressure. It acts as a vasodilator and thus lowers blood pressure by blocking the calcium channels in smooth vascular muscle.

Also, isradipine has a very good effect with high blood pressure profile over a period of 24 hours.

It belongs to the type of nifedipine calcium channel blockers such as nitrendipine and felodipine and also causes a strong vasodilatation with little effect on the heart.

Isradipine is administered orally. In studies of over 200 patients, the systolic blood pressure in the resting phase was reduced by 20 mmHg and diastolic values were reduced by about 10 mmHg.

Side effects of isradipine

Isradipine as calcium channel blockers for high blood pressure

In hypertension, calcium channel blockers such as isradipine can be prescribed

Side effects include gingival overgrowth, headaches, dizziness, nausea, intestinal discomfort, leg cramps, hot flashes and edema. Also fatigue and cramps in the legs may occur.

Itching or hives, impotence, palpitations, low blood pressure, joint pain, nervousness, strong seizures, jaundice, respiratory distress and diarrhoea are also possible.


When co-administered with beta-blockers and diuretics, it can cause a severe drop in blood pressure and heart failure can occur.


- LornirĀ® in divisible tablets 2.5 mg



Here you can read more about the calcium antagonist lacidipine and its application in high blood pressure.

Side effects of calcium channel blocker isradipine

Various types of calcium channel blockers

In general there are 2 different types of calcium antagonists (calcium channel blockers), namely the non-dihydropyridine and the dihydropyridines.

Non-dihydropyridines are:

- diltiazem

Dihydropyridines are:

- Felodipine
- Isradipine
- Lacidipine
- Lercanidipine

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