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Lacidipin with high blood pressure

Lacidipine in hypertensive patients

Lacidipine is a calcium channel blocker and is used in the treatment of high blood pressure and belongs to the so-called nifedipine-type. However, it can be distinguished from nifedipine by a higher lipophilicity.

Lacidipine blocks the channels in the vascular smooth muscle, thus preventing the influx of calcium into the muscle cells and thereby expands the arteries resulting in an improved blood flow and associated drop in blood pressure.

In essential hypertension motens® is allowed to treat mild to moderate essential hypertension and Carmen® and Corifeo® are also used. The active substance lacidipine should be taken orally and has a starting dose of 2 mg daily, but the dose may increase to 20 mg.

The calcium channel blocker lacidipine

Lacidipine and hypertension

In hypertension, calcium antagonists, such as lacidipine may be prescribed

The drug lacidipine and the medicinal products manufactured from it can be used in combination with beta-blockers, but it can also be used with ACE inhibitors and diuretics.

Combining lacidipine with diuretics may produce a hypotensive effect.

Side effects are similar to the usual calcium blocker issues including nausea, dizziness, diarrhea, faster heartbeat, palpitations, skin problems such as itching, redness and hives, edema, swelling in the ankles and legs, severe drop in blood pressure, heart attack and renal impairment. Women may also notice an increase in breast size.

Pregnant and lactating women shouldn’t take lacidipine.

Drugs:

- Carmen® (tablets with 2 and 4 mg)

- Corifeo® (tablets with 2 and 4 mg)

- Motens® (tablets with 2 and 4 mg)

 

 

Here you can read more about the calcium antagonist lercanidipine and its application in high blood pressure.




The calcium channel blocker lacidipine




Various types of calcium channel blockers

In general there are 2 different types of calcium antagonists (calcium channel blockers), namely the non-dihydropyridine and the dihydropyridines.

Non-dihydropyridines are:

- diltiazem
gallopamil
verapamil

Dihydropyridines are:

Amlodipine
Clevidipine
- Felodipine
- Isradipine
- Lacidipine
- Lercanidipine
Manidipine
Nicardipine
Nifedipine
Nilvadipine
Nimodipine
Nisoldipine
Nitrendipine




What kind of drugs for treating high blood pressure?