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High blood pressure - Nebivolol

Hypertension - Nebivolol

Nebivolol is one of the drugs that are used to treat high blood pressure. This substance consists of two enantiomers, which is a so-called common race mate. Both enantiomers control their contribution and lower the blood pressure.

It isn’t only used with hypertension, but also in mild to moderate chronic heart failure. Nebivolol is taken orally with water. Manufacturer names for this drug are Bystolic or Nebilox.

The name may vary depending on the manufacturer.

Mechanism of Action

Nevivolol contains not one, but two entire mechanisms of action, which should help against high blood pressure. The first enantiomer, i.e. the D-nebivolol is highly selective and sits down at the β1-adrenoceptors, thereby blocking them.

Nebivolol beta-blockers

Solutions for high blood pressure - the beta-blocker nebivolol

The beta-blocker nebivolol is used to treat high blood pressure

This mechanism occurs especially in high blood pressure of the 2nd generation. L-nebivolol adheres to a middle of the 3rd generation to the vessels of the endothelial cells.

It comes through that attachment to a vasodilatation, which is favored by the release of nitric oxide. By the vasodilator effect hemodynamics is promoted and there is a better circulation within the micropores and macro vessels. The same mechanism is adopted by the beta-blocker celiprolol.

Side effects

Hypertension can be well controlled, but there are also some side effects that cannot be ignored. Very often patients suffer from headaches and dizziness.

It is rare to experience nausea, upset stomachs and fatigue. It can also cause blurred vision and also slow the heart rate.

If you suffer from severe side-effects, you should contact your doctor.

Interactions of Nebivolol

Pharmaceutical interactions with substances can also be metabolized by the CYP2D6 isoenzyme.

Concomitant use of negative inotropic and negative chronotropic agents such as verapamil or diltiazem should be avoided as this can lead to severe and even dangerous interactions that can affect the heart and the entire circulatory system.

This drug should not be taken if you have an allergy to the active ingredient, if hepatic insufficiency or severe heart failure is present, or if the patient has severe bronchial obstruction.

Here you can read more about the beta blocker penbutolol in its use to treat high blood pressure.

Nebivolol as a beta blocker

Interactions of nebivolol

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