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Hypertension - Quinapril suffering high blood pressure

Quinapril is a medication for high blood pressure, which was classified according to its mode of action as an ACE inhibitor.

Mode of action:

ACE (Angiotensin Converting Enzyme) is an enzyme that allows the conversion of angiotensin I to angiotensin II.

Angiotensin II is a direct cause of high blood pressure.

They also indirectly inhibit the excretion of water, whereby its effect is increased even more.

An ACE inhibitor blocks the ACE particles and thus accelerates the production of angiotensin II.

The main effect of ACE inhibitor therapy is the lowering of blood pressure.

This happens due to the diuretic and vasodilator effect of Quinapril.

In addition, the drug decreases aldosterone synthesis and its secretion.

Since the ACE affects sodium and potassium in the body, quinapril also increases sodium excretion and promotes the retention of potassium from the urine.



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Application of Quinapril as ACE inhibitors

The ACE inhibitor quinapril in use against hypertension
Quinapril in hypertension

Quinapril ACE inhibitors as an antihypertensive

Because of its effect of ACE inhibitors they are often used in the treatment of hypertension, heart failure and in the treatment of patients after myocardial infarction.

Side effects:

However quinapril generates a series of the typical side effects of ACE inhibitors.

One of the most frequently occurring side effects is a dry cough also known as the ACE inhibitor cough.

In most cases, the hypertension is further treated with substances from Sartan group.

Many patients develop skin allergies from these types of drugs.

In such a case, a massive swelling of the subcutaneous tissue or even a swelling of the mucosa can occur.

This can sometimes be life-threatening.




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Side effects of quinapril and other ACE - inhibitors

Other less dangerous unwanted effects of this treatment of hypertension are skin lesions and taste disturbances.

Interactions:

Contraindications for use of ACE inhibitors include:

- Constriction of renal vessels

- Severe narrowing of the main arteries

- Obstructive cardiomyopathy (a disease of the heart muscle)

- And of course, hypotension (low blood pressure)

Quinapril should not be taken by women who are lactating or are pregnant.

There are also numerous interactions with other drugs available.

This group includes mainly remedies for hypothyroidism and hypertension, but also the potassium-sodium affecting drugs.




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ACE inhibitors in an overview

Other drugs in this group are listed here alphabetically. 

For more information, simply click on the link

Benazepril (Lotensin)

Captopril (Capoten)

Cilazapril

Enalapril (Vasotec)

Fosinopril (Monopril)

Lisinopril (Prinivil, Zestril)

Moexipril

Perindopril

Quinapril (Accupril)

Ramipril (Altace)

Spirapril

Trandolapril

Zofrenopril

Also note that the ACE inhibitors are often used in combination with other blood pressure lowering drugs. 

Here you read about the so-called combination therapy in hypertension.


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