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Verapamil with high blood pressure

High blood pressure and verapamil

Verapamil is used for hypertension and cardiovascular diseases.

A complicated system of different messengers ensures that the blood pressure is adjusted to cater for every kind of situation. For example, a lower blood pressure is required when the body comes to rest through sleep in order to supply the tissues with the necessary nutrients and oxygen.

For sports activities, however, a higher demand for oxygen and nutrients is required to ensure an adequate supply. Therefore the pressure increases. Calcium as a mineral substance has been an important factor.

Blood vessels are surrounded by muscle cells, whose activity is controlled by calcium.

Some signals in the cell wall of the muscle cell to ensure that calcium flows into the cell. The calcium then triggers the contraction of the muscles, thereby narrowing the vessels and the blood pressure rises.

Mode of action of verapamil

Verapamil as a calcium channel blocker for hypertension

Verapamil as calcium channel blockers for high blood pressure

As a calcium antagonist, verapamil blocks the channels in the wall of the vascular musculature and prevents the inflow of calcium. Thus, the muscle can relax and the blood vessels to widen.

With this improved blood circulation, hypertension can be controlled.

The drug verapamil facilitates the action of the heart, because it expands the blood vessels that supply the heart with oxygen. The drug also causes an improvement if there are signs of heart narrowness. It also acts directly on the heart muscle. By blocking calcium channels, the heart beats slower and the pulse calms down and the blood pressure returns to normal. This drug can also help with heart rhythm disorders, if they are linked with excessive pulse.

In summary, the drug Verapamil is used to treat the following diseases/disorders:

  • For the regulation of high blood pressure/hypertension
  • To normalize the heartbeat cardiac arrhythmia and to expand the vessels
  • For the treatment of various forms of angina pectoris and myocardial infarction in coronary heart diseases

The calcium channel blocker verapamil

Verapamil for hypertension and some cardiovascular complaints are available from different manufacturers. The following trade names are currently available:

Tarka Isoptin, Vera, Vera gamma, verapamil, Vera Hexal, Veramex, Veratide and Veroptinstada. 

These medicines for high blood pressure are available in different dosage strengths.

Since August 2012, this medication has also been used against cluster headaches.

Verapamil may also cause side effects and interactions with other medicines. Before taking this medication your doctor should inform you about any possible side effects.

Here you can read more about the calcium antagonist amlodipine and its application in high blood pressure.




Mode of action of verapamil




The calcium channel blocker verapamil




Various types of calcium channel blockers

In general there are 2 different types of calcium antagonists (calcium channel blockers), namely the non-dihydropyridine and the dihydropyridines.

Non-dihydropyridines are:

- diltiazem
gallopamil
verapamil

Dihydropyridines are:

Amlodipine
Clevidipine
- Felodipine
- Isradipine
- Lacidipine
- Lercanidipine
Manidipine
Nicardipine
Nifedipine
Nilvadipine
Nimodipine
Nisoldipine
Nitrendipine




What kind of drugs for treating high blood pressure?